Description

Ipamorelin represents a highly selective synthetic pentapeptide growth hormone secretagogue developed through systematic peptide engineering to optimize growth hormone releasing activity. The compound exhibits the molecular formula C38H49N9O5 with a molecular weight of 711.85 g/mol and is catalogued under CAS number 170851-70-4. The peptide sequence consists of five amino acids arranged as Aib-His-D-2-Nal-D-Phe-Lys-NH2, where Aib represents α-aminoisobutyric acid and D-2-Nal represents D-2-naphthylalanine. The structural design incorporates specific modifications to enhance selectivity and potency for growth hormone secretagogue receptor 1a (GHS-R1a). Originally developed by Novo Nordisk, Ipamorelin has been extensively characterized in laboratory systems and demonstrates consistent growth hormone releasing potency and efficacy in research models.